HYPERURICEMIA – Uric acid symptoms, Causes, Treatment

Image by cnick from Pixabay

HIGH URIC ACID LEVEL

Uric acid derived from purines. It usually excreted from the body by the kidney. Normal serum uric acid level is 3.5-7 mg/dl in males and 2.5-6 mg/dl in females.

CAUSES

PRIMARY – Uric acid level increases due to excess uric acid production in our body from purine or reduced uric acid excretion by the kidney.

SECONDARY –

  • Diuretics
  • Alcoholism
  • Obesity
  • High purine diet
  • Renal failure
  • Hypothyroidism
  • Psoriasis
  • Chemotherapy for cancer

SYMPTOMS

Hyperuricemia usually asymptomatic and diagnosed during a routine blood test. Sometimes, uric acid forms crystals and accumulates in joints causing gout. Gout is a very painful arthritis and characterized by redness, tenderness, and swelling of the joint. Excess uric acid may accumulate in the kidney and forms a renal stone.

Food should be avoided –

  • Alcohol
  • Mushroom
  • Red Meat
  • Organ meats like liver
  • Pea
  • Cauliflower
  • Beans
  • Sea fish

TREATMENT

For an acute attack of gout, first joint pain is relieved by NSAIDs like Ibuprofen, Indomethacin, naproxen, etc. In the case of a severe gout attack, corticosteroid or colchicine is used. After remission of acute attack drugs likes to reduce uric acid allopurinol, Febuxostat is used. These drugs are xanthine oxidase inhibitors. That inhibits uric acid production in our bodies. These drugs are xanthine oxidase inhibitors that inhibit uric acid production in our bodies. Allopurinol can cause rashes and lower blood cell count. Febuxostat has toxicity to the liver. Uricosuric drugs lower serum uric acid by increasing its excretion through the kidney. Probenecid and Lesinurad are important uricosuric drugs.


6 Replies to “HYPERURICEMIA – Uric acid symptoms, Causes, Treatment”

  1. My partner and I stumbled over here by a different web address and thought I should check things out. I like what I see so i am just following you. Look forward to going over your web page repeatedly.

  2. Definitely believe that which you said. Your favorite reason seemed to be on the web the easiest thing to be aware of. I say to you, I certainly get irked while people think about worries that they just don’t know about. You managed to hit the nail upon the top and defined out the whole thing without having side-effects , people could take a signal. Will likely be back to get more. Thanks

Leave a Reply

Your email address will not be published. Required fields are marked *